Cevidoplenib dimesylate

CAS No. 2043659-93-2

Cevidoplenib dimesylate( —— )

Catalog No. M28223 CAS No. 2043659-93-2

Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 282 Get Quote
10MG 447 Get Quote
25MG 714 Get Quote
50MG 1017 Get Quote
100MG 1368 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    Cevidoplenib dimesylate
  • Note
    Research use only, not for human use.
  • Brief Description
    Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.
  • Description
    Cevidoplenib dimesylate is an inhibitor of spleen tyrosine kinase (Syk), possessing anti-inflammatory and immunomodulating properties.(In Vitro):Cevidoplenib dimesylate inhibits the activity of SYK through binding to SYK, blocking Fc receptor and B-cell receptor (BCR)-mediated signaling in inflammatory cells, including macrophages, neutrophils, mast cells, natural killer (NK) cells, and B cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Syk
  • Recptor
    HSF1
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2043659-93-2
  • Formula Weight
    665.74
  • Molecular Formula
    C27H35N7O9S2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 25 mg/mL (37.55 mM)
  • SMILES
    CC1=NN(C2=NC(NC3=CC4=C(N(C)C=C4C(C5CC5)=O)C=C3)=NC=C2)C=C1CN6C[C@H](O)CO6.CS(=O)(O)=O.CS(=O)(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Keith Jones, et al. Fused 1,4-dihydrodioxin derivatives as inhibitors of heat shock transcription factor 1. WO2015049535A1.
molnova catalog
related products
  • OXSI-2

    OXSI-2 is an inhibitor of Syk with an EC50 of 313 nM and an IC50 of 14 nM. OXSI-2 completely inhibits Adaptor protein LAT Y191 phosphorylation and Syk mediated events in platelets.

  • Mitapivat

    Mitapivat, also known as PKM2 activator 1020 is a PKM2 activator (pyruvate kinase activator) for the treatment of pyruvate kinase deficiency.

  • BAY 61-3606 dihydroc...

    A potent, ATP-competitive, reversible, and highly selective inhibitor of Syk tyrosine kinase with Ki of 7.5 nM.